The Snijder lab contributed to a wonderful study published in Nature, led by Jarrod Shilts and Gavin Wright from the Wellcome Sanger Institute, and in collaboration with others:
A physical wiring diagram for the human immune system | Nature
The study combines careful protein-protein interaction analysis of proteins expressed on the surface of immune cells with pharmacoscopy-based measurement of how those proteins perturb cell-cell contacts among immune cells. On our side, this work was performed by Yannik Severin, using his beautiful single-round multiplexed immunofluorescence protocol to perform image-based screening of human immune cells detailed on bioarxiv.
Also be sure to check out the great write-up by the ETH Zurich News team and wonderful Twitter posts by Jarrod Shilts and Eric Topol.